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• Activity deltas table
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Motif ID: FOX{D1,D2}.p2

Z-value: 1.292

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_161193190	4.935		APOA2	apolipoprotein A-II
chr10_+_63808968	4.339	NM_001244638	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr1_-_161193375	4.193	NM_001643	APOA2	apolipoprotein A-II
chr12_-_9268440	4.096		A2M	alpha-2-macroglobulin
chr12_-_9268513	3.939		A2M	alpha-2-macroglobulin
chr12_-_9268522	3.488	NM_000014	A2M	alpha-2-macroglobulin
chr10_-_101841593	3.361	NM_001308	CPN1	carboxypeptidase N, polypeptide 1
chr17_-_64225496	3.085	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr5_-_42811959	3.070	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr12_-_9268475	2.980		A2M	alpha-2-macroglobulin
chr11_-_115375065	2.850	NM_001098517 NM_014333	CADM1	cell adhesion molecule 1
chr2_-_188419185	2.737	NM_001032281 NM_006287	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr17_-_7017971	2.460		ASGR2	asialoglycoprotein receptor 2
chr7_+_134832765	2.457	NM_018295	TMEM140	transmembrane protein 140
chr10_-_45474210	2.273	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr10_+_63661012	2.224	NM_032199	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr8_-_119123804	2.169	NM_000127	EXT1	exostosin 1
chr17_-_7018049	2.079	NM_001181 NM_001201352 NM_080912 NM_080913	ASGR2	asialoglycoprotein receptor 2
chr11_+_73359734	1.982	NM_001130036	PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1
chr7_+_134464417	1.880		CALD1	caldesmon 1
chr17_+_72427535	1.832	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr6_+_89791510	1.799		PNRC1	proline-rich nuclear receptor coactivator 1
chr1_-_20812727	1.790	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_+_18496966	1.775	NM_004864	GDF15	growth differentiation factor 15
chr1_-_92351613	1.719	NM_001195683 NM_003243	TGFBR3	transforming growth factor, beta receptor III
chr7_+_134464161	1.706	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr2_-_165551178	1.654		COBLL1	COBL-like 1
chr1_-_92351476	1.645		TGFBR3	transforming growth factor, beta receptor III
chr9_-_94124194	1.642	NM_001698	AUH	AU RNA binding protein/enoyl-CoA hydratase
chr10_-_90750955	1.634	NM_001141945	ACTA2	actin, alpha 2, smooth muscle, aorta
chr3_-_149086884	1.630		TM4SF1	transmembrane 4 L six family member 1
chr9_-_94124149	1.628		AUH	AU RNA binding protein/enoyl-CoA hydratase
chr7_-_87342569	1.549	NM_000927	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr10_-_52645384	1.537		A1CF	APOBEC1 complementation factor
chr13_+_113777112	1.527	NM_000504	F10	coagulation factor X
chr3_-_124605840	1.510		ITGB5	integrin, beta 5
chr4_+_124317884	1.504	NM_199327	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr8_+_40010986	1.485	NM_020130	C8orf4	chromosome 8 open reading frame 4
chr10_-_52645430	1.480	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr3_-_93692898	1.462	NM_000313	PROS1	protein S (alpha)
chr3_-_149421059	1.454	NM_001168278	WWTR1	WW domain containing transcription regulator 1
chr15_+_99191671	1.390		IGF1R	insulin-like growth factor 1 receptor
chr22_+_38599026	1.307	NM_001161573	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr2_+_97481977	1.301	NM_017623 NM_199078	CNNM3	cyclin M3
chr3_-_93692592	1.298		PROS1	protein S (alpha)
chr7_+_94539209	1.280	NM_001166161 NM_001166162 NM_001166163	PPP1R9A	protein phosphatase 1, regulatory subunit 9A
chr1_-_57045129	1.228		PPAP2B	phosphatidic acid phosphatase type 2B
chr3_+_187930720	1.220	NM_005578	LPP	LIM domain containing preferred translocation partner in lipoma
chr3_+_23987514	1.192	NM_001145425	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr14_-_74551159	1.171	NM_005589	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr2_-_188419049	1.161		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr11_+_22696318	1.155	NM_005256	GAS2	growth arrest-specific 2
chr1_-_27240430	1.110	NM_021969	NR0B2	nuclear receptor subfamily 0, group B, member 2
chr20_+_306205	1.081	NM_006943	SOX12	SRY (sex determining region Y)-box 12
chr8_-_134309448	1.073	NM_001135242 NM_006096	NDRG1	N-myc downstream regulated 1
chr20_+_45338125	1.065	NM_030777	SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10
chr14_-_74551073	1.032		ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr1_+_229440128	1.029	NM_006542	SPHAR	S-phase response (cyclin related)
chr10_+_7745284	1.027		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr22_+_21128378	1.017	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr3_-_99833348	1.015	NM_001042459 NM_182909	FILIP1L	filamin A interacting protein 1-like
chr20_-_50384899	1.006	NM_006045	ATP9A	ATPase, class II, type 9A
chr18_+_66465316	0.989	NM_024781	CCDC102B	coiled-coil domain containing 102B
chr14_+_23067128	0.987	NM_022060	ABHD4	abhydrolase domain containing 4
chr1_-_93342706	0.978	NM_001252271	FAM69A	family with sequence similarity 69, member A
chr17_+_37896219	0.970	NM_001242443	GRB7	growth factor receptor-bound protein 7
chr2_-_165424993	0.967		GRB14	growth factor receptor-bound protein 14
chr18_-_500583	0.963	NM_130386	COLEC12	collectin sub-family member 12
chr5_-_16742336	0.954		MYO10	myosin X
chr3_-_114343052	0.953	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr6_+_17600504	0.943	NM_016255	FAM8A1	family with sequence similarity 8, member A1
chr3_-_185826748	0.931	NM_004454	ETV5	ets variant 5
chr5_-_111091947	0.926	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr8_+_126442557	0.918	NM_025195	TRIB1	tribbles homolog 1 (Drosophila)
chr20_-_50384861	0.917		ATP9A	ATPase, class II, type 9A
chrY_+_2709596	0.909	NM_001008	RPS4Y1	ribosomal protein S4, Y-linked 1
chr14_-_94789641	0.891	NM_001756	SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr1_-_60392461	0.890		CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2
chr10_-_54531394	0.864	NM_000242	MBL2	mannose-binding lectin (protein C) 2, soluble
chr10_+_111985628	0.860	NM_005962	MXI1	MAX interactor 1
chr2_-_190044330	0.859	NM_000393	COL5A2	collagen, type V, alpha 2
chr2_+_74120132	0.858		ACTG2	actin, gamma 2, smooth muscle, enteric
chr1_+_207277577	0.855	NM_000715	C4BPA	complement component 4 binding protein, alpha
chr1_+_227127959	0.843		ADCK3	aarF domain containing kinase 3
chr11_+_46402333	0.842	NM_001012334	MDK	midkine (neurite growth-promoting factor 2)
chr1_+_227127993	0.828		ADCK3	aarF domain containing kinase 3
chr2_+_74120092	0.828	NM_001199893 NM_001615	ACTG2	actin, gamma 2, smooth muscle, enteric
chr10_+_123922940	0.827		TACC2	transforming, acidic coiled-coil containing protein 2
chr1_+_227127999	0.825		ADCK3	aarF domain containing kinase 3
chr9_-_136933091	0.818	NM_007371	BRD3	bromodomain containing 3
chr1_-_24469571	0.811	NM_021258	IL22RA1	interleukin 22 receptor, alpha 1
chrY_+_2709630	0.800		RPS4Y1	ribosomal protein S4, Y-linked 1
chr16_-_57318574	0.799	NM_015993	PLLP	plasmolipin
chr1_-_86043932	0.799	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr2_-_65593866	0.785	NM_001128210	SPRED2	sprouty-related, EVH1 domain containing 2
chr10_+_111969988	0.782	NM_001008541	MXI1	MAX interactor 1
chr1_-_12677347	0.774	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr9_-_136933552	0.773		BRD3	bromodomain containing 3
chr15_-_60884615	0.766	NM_134262	RORA	RAR-related orphan receptor A
chr17_+_2680349	0.754		RAP1GAP2	RAP1 GTPase activating protein 2
chr8_-_12973752	0.753	NM_001164271	DLC1	deleted in liver cancer 1
chr12_-_91576805	0.749	NM_001920	DCN	decorin
chr6_-_131321868	0.747	NM_001252660	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr10_+_7745325	0.743		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr10_-_90712510	0.740	NM_001613	ACTA2	actin, alpha 2, smooth muscle, aorta
chr2_-_216259197	0.739		FN1	fibronectin 1
chr14_+_24584009	0.738		DCAF11	DDB1 and CUL4 associated factor 11
chr1_+_227127937	0.734	NM_020247	ADCK3	aarF domain containing kinase 3
chr20_-_34241830	0.729	NM_003915	CPNE1	copine I
chr10_-_92681025	0.720	NM_014391	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr20_+_62887046	0.716	NM_001104925 NM_018257	PCMTD2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr7_+_134464372	0.715		CALD1	caldesmon 1
chr1_+_145438437	0.711	NM_006472	TXNIP	thioredoxin interacting protein
chr10_+_7745229	0.708	NM_002216	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr1_-_169555710	0.708	NM_000130	F5	coagulation factor V (proaccelerin, labile factor)
chr3_-_58522873	0.704	NM_003500	ACOX2	acyl-CoA oxidase 2, branched chain
chr17_+_53344966	0.703		HLF	hepatic leukemia factor
chr3_+_23986735	0.695	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr2_+_11674241	0.693	NM_014668	GREB1	growth regulation by estrogen in breast cancer 1
chr14_+_24584321	0.690		DCAF11	DDB1 and CUL4 associated factor 11
chr10_+_123923104	0.688	NM_006997 NM_206860	TACC2	transforming, acidic coiled-coil containing protein 2
chr4_+_155484131	0.686	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr22_-_31686707	0.686		PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr1_+_171154387	0.685	NM_001460	FMO2	flavin containing monooxygenase 2 (non-functional)
chr16_-_57318452	0.667		PLLP	plasmolipin
chr1_+_64088886	0.666	NM_001172818	PGM1	phosphoglucomutase 1
chr14_+_24583979	0.665	NM_025230	DCAF11	DDB1 and CUL4 associated factor 11
chr17_+_41052813	0.664	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr14_+_24583905	0.654	NM_001163484	DCAF11	DDB1 and CUL4 associated factor 11
chr6_+_64356430	0.653	NM_015153	PHF3	PHD finger protein 3
chr1_-_60392324	0.646	NM_000775	CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2
chr3_+_54156691	0.646	NM_018398	CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr19_-_7293876	0.635	NM_000208 NM_001079817	INSR	insulin receptor
chr20_+_44035203	0.624	NM_001048223 NM_001048224	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_+_140587086	0.621		MGST2	microsomal glutathione S-transferase 2
chr6_+_64345977	0.619		PHF3	PHD finger protein 3
chr13_-_41240607	0.617	NM_002015	FOXO1	forkhead box O1
chr1_-_169555624	0.615		F5	coagulation factor V (proaccelerin, labile factor)
chr12_-_91576579	0.612		DCN	decorin
chr1_+_151630710	0.612		SNX27	sorting nexin family member 27
chr4_+_140586921	0.609	NM_001204366 NM_001204367 NM_001204368 NM_002413	MGST2	microsomal glutathione S-transferase 2
chr13_-_48987247	0.606		LPAR6	lysophosphatidic acid receptor 6
chr6_-_122792881	0.600	NM_020755	SERINC1	serine incorporator 1
chr10_+_31610063	0.595	NM_001128128 NM_001174094	ZEB1	zinc finger E-box binding homeobox 1
chr6_+_64345726	0.594		PHF3	PHD finger protein 3
chr6_+_123110345	0.587		SMPDL3A	sphingomyelin phosphodiesterase, acid-like 3A
chr18_+_60382617	0.586	NM_194449	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1
chr1_-_173886464	0.573	NM_000488	SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr1_-_20306908	0.571	NM_000300 NM_001161727 NM_001161728	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)
chr2_-_218843541	0.568		TNS1	tensin 1
chr16_+_55512801	0.559	NM_004530	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr3_+_54156573	0.557		CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr20_-_43150592	0.551		SERINC3	serine incorporator 3
chr12_-_71551564	0.547		TSPAN8	tetraspanin 8
chr6_+_12290528	0.543	NM_001168319 NM_001955	EDN1	endothelin 1
chr12_-_71551778	0.543	NM_004616	TSPAN8	tetraspanin 8
chr7_+_65419441	0.541		VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr12_-_57704245	0.538	NM_014925	R3HDM2	R3H domain containing 2
chr16_+_20420854	0.534	NM_017888	ACSM5	acyl-CoA synthetase medium-chain family member 5
chr17_-_26662439	0.534	NM_174887	IFT20	intraflagellar transport 20 homolog (Chlamydomonas)
chr17_-_65241276	0.533		HELZ	helicase with zinc finger
chr3_-_125820390	0.532	NM_001164475	SLC41A3	solute carrier family 41, member 3
chr14_+_50234907	0.530		KLHDC2	kelch domain containing 2
chr7_+_149570004	0.525	NM_001100592 NM_145230	ATP6V0E2	ATPase, H+ transporting V0 subunit e2
chr4_-_103682126	0.522		MANBA	mannosidase, beta A, lysosomal
chr19_+_35630391	0.518	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr13_-_38443859	0.517	NM_001135955 NM_001135956 NM_001135957 NM_001135958 NM_003306 NM_016179	TRPC4	transient receptor potential cation channel, subfamily C, member 4
chrY_+_16635625	0.516	NM_014893	NLGN4Y	neuroligin 4, Y-linked
chr20_+_21106623	0.513	NM_001163022 NM_001163023 NM_018474	PLK1S1	polo-like kinase 1 substrate 1
chr6_+_64345709	0.513		PHF3	PHD finger protein 3
chr3_-_79817058	0.512	NM_002941	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr20_-_43150673	0.512		SERINC3	serine incorporator 3
chr11_+_101983170	0.511	NM_001195045	YAP1	Yes-associated protein 1
chr3_-_187452669	0.501	NM_001134738	BCL6	B-cell CLL/lymphoma 6
chr5_+_102201526	0.500	NM_000919 NM_001177306 NM_138766 NM_138821 NM_138822	PAM	peptidylglycine alpha-amidating monooxygenase
chr22_-_31688329	0.497	NM_001135911 NM_052880	PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr17_+_58755158	0.497	NM_001099432 NM_017679	BCAS3	breast carcinoma amplified sequence 3
chr10_+_123748688	0.493	NM_206861 NM_206862	TACC2	transforming, acidic coiled-coil containing protein 2
chr2_-_165478357	0.492	NM_004490	GRB14	growth factor receptor-bound protein 14
chr12_-_53343607	0.489		KRT8	keratin 8
chr6_+_64345672	0.485		PHF3	PHD finger protein 3
chr20_-_43150686	0.485	NM_006811 NM_198941	SERINC3	serine incorporator 3
chr11_+_22688156	0.484	NM_001143830	GAS2	growth arrest-specific 2
chr19_+_35629727	0.484	NM_021902	FXYD1	FXYD domain containing ion transport regulator 1
chr14_+_24584467	0.472	NM_181357	DCAF11	DDB1 and CUL4 associated factor 11
chr1_-_115053677	0.471		TRIM33	tripartite motif containing 33
chr19_+_41725098	0.466	NM_001699 NM_021913	AXL	AXL receptor tyrosine kinase
chr16_-_57831675	0.465	NM_001130099	KIFC3	kinesin family member C3
chr12_+_100867550	0.465	NM_001206977 NM_001206978 NM_001206979 NM_005123	NR1H4	nuclear receptor subfamily 1, group H, member 4
chr10_-_92680784	0.464		ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr2_+_102508333	0.457		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr16_-_75467249	0.452	NM_006324	CFDP1	craniofacial development protein 1
chr16_-_48399753	0.450		SIAH1	seven in absentia homolog 1 (Drosophila)
chr10_+_7745354	0.444		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr16_+_67571980	0.443		FAM65A	family with sequence similarity 65, member A
chr12_+_121416548	0.441	NM_000545	HNF1A	HNF1 homeobox A
chr7_+_106809405	0.440	NM_001244262 NM_012257	HBP1	HMG-box transcription factor 1
chr14_+_50234783	0.439	NM_014315	KLHDC2	kelch domain containing 2
chr17_+_57642885	0.433	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr1_-_57045235	0.433	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
14.12	1.27e-03	GO:0051346	negative regulation of hydrolase activity

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
5.48	2.35e-03	GO:0030054	cell junction
9.37	1.52e-02	GO:0070161	anchoring junction
11.24	3.59e-02	GO:0030055	cell-substrate junction

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
8.69	1.17e-03	GO:0004857	enzyme inhibitor activity
12.19	4.61e-03	GO:0004866	endopeptidase inhibitor activity
11.98	5.02e-03	GO:0030414	peptidase inhibitor activity
11.67	5.68e-03	GO:0061135	endopeptidase regulator activity
17.76	6.43e-03	GO:0004867	serine-type endopeptidase inhibitor activity
9.64	1.41e-02	GO:0061134	peptidase regulator activity